Application of Surface-active Agents to Pharmaceutical Preperations. IX

Surfactants - Surface Active Agents

The definition for a detergent is a cleaning agent. The main cleaning agent used in earlier days was soap. This term means a compound formed from the reaction of a fatty acid with a base such as caustic soda, forming the sodium soap of the acid. The more commonly used cleaning agent in this day and age is the synthetic detergent (SYNDET) which is a formulation such as TIDE or FAB. The essential...

Silicone Surface-Active Agents

Survivor Curves of Bacteria Exposed to Surface-active Agents.

Reports on bacterial death studies since the basic work of Kronig and Paul (1896) have generally recognized that the death process of bacteria exposed to unfavorable environmental conditions follows a uniform and consistent course. The constancy of the rate of death is the outstanding feature; the term, "constant death rate," means that the number of bacteria that die per time unit is a constan...

Surface active agents as tumor promoters.

*TUC Centenary Institute of Occupational Health London School of Hygiene and Tropical Medicine, Keppel St., London WC1E-7HT, England. the types of promoter listed have not been demonstrated as such by animal experiments, but if a substance is a carcinogenic but not mutagenic, then it is most probably a tumor promoter. This assumes that mutagens are initiators and that promoters can induce cance...

Surface-active agents from two bacillus species.

Two Bacillus species were studied which produced bioemulsifiers; however, they were distinctly different compounds. Bacillus sp. strain IAF 343 produced unusually high yields of extracellular biosurfactant when grown on a medium containing only water-soluble substrates. The yield of 1 g/liter was appreciably better than those of most of the biosurfactants reported previously. This neutral lipid...